RNA-SEQ OF THE CARIBBEAN REEF-BUILDING CORAL ORBICELLA FAVEOLATA (SCLERACTINIA-MERULINIDAE) UNDER BLEACHING AND DISEASE STRESS EXPANDS MODELS OF CORAL INNATE IMMUNITY

Climate change-driven coral disease outbreaks have led to widespread declines in coral populations.Early work on coral genomics established that corals have a complex innate immune system, and whole-transcriptome gene expression studies have revealed mechanisms by which the coral immune system responds to stress and disease.The present investigatio

Cancer transformation involves reprograming of mitochondrial function to read more avert cell death mechanisms, monopolize energy metabolism, accelerate mitotic proliferation, and promote metastasis.Mitochondrial ion channels are emerging as promising therapeutic targets mainly because of their connection to metabolic and apoptotic functions.This m

Abstract Background Documentation of critical data elements is a focus of the Pediatric Rheumatology Care and Outcomes Improvement Network to aid in clinical care and research for patients with juvenile idiopathic arthritis.We aimed to increase data capture for critical data elements and hypothesized that quality improvement methodology would impro